Updated · United States & Canada
GLP-1, weight-loss and diabetes medicines — explained clearly
Approvals, label dosing, side effects, costs and the legal ways to get every GLP-1, incretin and insulin medicine in the United States and Canada.
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- medicines
- 26
- comparisons
- 6
- answered questions
- 28
- buying & safety guides
- 6
What is a GLP-1?
A GLP-1 receptor agonist is a medicine that mimics the gut hormone GLP-1: it raises insulin after meals, lowers glucagon, slows stomach emptying and reduces appetite. Semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) are the best known; all are prescription-only in the US and Canada. Read the full answer →
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All 26 medicines →GLP-1 & incretin medicinesWegovy (injection)semaglutide · Once weeklyGLP-1 & incretin medicinesZepboundtirzepatide · Once weeklyGLP-1 & incretin medicinesOzempic (injection)semaglutide · Once weeklyGLP-1 & incretin medicinesMounjarotirzepatide · Once weeklyGLP-1 & incretin medicinesWegovy pilloral semaglutide 25 mg · Once dailyGLP-1 & incretin medicinesFoundayoorforglipron · Once daily
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Top questions
All questions →- What if I miss an Ozempic dose?
- What if I miss a Wegovy dose?
- What if I miss a Zepbound or Mounjaro dose?
- What if I miss a Trulicity dose?
- Can you drink alcohol on Ozempic, Wegovy or Zepbound?
- How long does semaglutide stay in your system?
- How long does tirzepatide stay in your system?
- What is 'Ozempic face'?
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